Students across PNG have been boycotting lectures since the beginning of May while demanding the Prime Minister step down to face fraud allegations.
Vice-chancellor, Dr Albert Schram, said UNITECH's female students were leading the return to study.
"The female students all met yesterday and they decided all to go to classes. So that is a very, very positive development. And 40 percent of our student population is female so we have that group already onboard."
Albert Schram estimated the six week boycott had cost UNITECH about $US1.2 million which the university will try to absorb if the government does not provide additional funding.